A review also helps avoid the prescribing cascade, which involves a physician adding additional drugs to a patient's regimen to treat side effects of other medications. 20 In scenario 3, the patient's ankle edema may be a side effect of the calcium channel blocker that was prescribed to treat her hypertension. The hypertension may be a side effect of her pain medication. Planning regular monitoring for certain medications is important. In scenario 5, if the patient is on lisinopril, she will need follow-up serum chemistries to assess for hyperkalemia or increased serum creatinine.