Topical nonsteroidal anti-inflammatory drugs the importance of drug delivery and therapeutic outcome

1% Gel:
Lower Extremities: Apply 4 g to the affected foot, knee, or ankle 4 times a day and rub in gently; not to exceed 16 g/day to any single joint of the lower extremities

Upper Extremities: Apply 2 g to the affected hand, wrist, or elbow 4 times a day and rub in gently; not to exceed 8 g/day to any single joint of the upper extremities

Maximum dose: 32 g/day over all affected joints

Comments:
-When used on the lower extremities, this drug should be applied to the entire affected foot, knee, or ankle; the entire foot includes the sole, the top of the foot, and the toes.
-When used on the upper extremities, apply to the entire affected hand, wrist, or elbow; the entire hand includes the palm, the back of the hands, and the fingers.
-The accompanying dosing card should be used for application; consult manufacturer product information for instructions.

Use: For the relief of pain associated with osteoarthritis of the joints amenable to topical treatment, such as the knees and those of the hands; this drug has not been evaluated for use on the spine, hip, or shoulder

% Topical Solution: Apply 40 drops to each affected knee 4 times a day

2% Topical Solution: Apply 40 mg (2 pump actuations) to each affected knee 2 times a day

Use: For the relief of signs and symptoms of osteoarthritis of the knee(s)

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

If you do take an over the counter pain medication, be sure to follow the directions closely. In general, ibuprofen (Advil, Motrin), naproxen sodium (Aleve) or ketoprofen (Orudis KT) are helpful for those suffering from a sports injury that results in pain, swelling, and inflammation. Generic brands work in the same way and must meet the same standards as the brand name equivalent, but cost less. Read and follow the label directions and don't take more than the recommended dose. Also, don't use any OTC drugs for more than 10 days, unless your doctor or pharmacist tells you it's OK to do so.

Topical nonsteroidal anti-inflammatory drugs the importance of drug delivery and therapeutic outcome

topical nonsteroidal anti-inflammatory drugs the importance of drug delivery and therapeutic outcome

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