Mast-cell stabilizers prevent the release of chemical mediators of inflammation from the mast cells. These are effective for all eye allergies. The first of this class of drug was cromolyn sodium (Crolom or Opticrom), which is available OTC. This topical medicine has been effective for treating mild cases of vernal keratoconjunctivitis and probably mild allergic rhinoconjunctivitis and has no significant side effects. It does have a slow onset of action. The newer agent, lodoxamide (Alomide), is 2,500 times more potent than Crolom and has a faster onset of action. This prescription medicine may be used in children older than 2 years of age and has minimal side effects. One disadvantage is the need to use the drops four times a day, and long-term use is necessary to prevent symptoms.
“For several years I have suffered from Uveitis and Macula Odema in one eye. The Macula Odema has settled but the Uveitis is only controlled with Corticosteroid eye drops. I tried to gradually reduce the corticosteroid drops and replace them with the carnosine, but this was not entirely successful and after a visit to the Specialist I am back using the coticosteroid drops. I didn't know whether it would be of any value to use both at the same time. What the Carnosine did do was reduce the pressure and as both my parents had glaucoma I am very conscious of the need to keep the pressure down. So I may need to use the carnosine for that in the future and of course I realize that extended use of the steroid drops can cause cataracts.”