After cutting out all the junk and getting rid of products that might make users a little too jittery, we were finally able to arrive at our top picks. Of the remaining contenders, we favored those with the highest quantity of effective ingredients and the lowest quantity of superfluous nonsense. If there’s one word to describe our top picks, it’s “well-rounded.” These supplements don’t just rely on one ingredient to get the job done; they pull in everything from creatine to citrulline and round out the package with a nice kick of caffeine (or a milder stimulant like yerba mate).
Nitrosigine® is a novel form of arginine and silicon backed by clinical science that was recently presented at the 2014 Experimental Biology Scientific Meeting and also a highlight of the 2016 International Society of Sports Nutrition Annual Conference. In fact, Nitrosigine® is clinically shown to increase nitric oxide levels (measured as salivary nitrites).* What’s more, in the same human clinical trial, subjects had a significant increase in mean plasma arginine levels within one hour of their first dose. With more nitric oxide, your blood vessels will engorge with a rush of nutrient-rich blood, carrying oxygen, amino acids and naturally occurring anabolic compounds to your muscles.*